The research of NCoEDG requires establishment of common data structures and appropriate analytical methods. The partners have made a commitment of the data sharing of the phenotypes, collected genotypes and transcript profile information. The initial structure of this database already exists for transcript and genotype data and is at use between Uppsala and Lund/Malmö and will provide the basis for the shared database between the sites for three broad phenotypes. The integration of the collected data and use of statistical, biocomputing and database tools will be coordinated by the expert team at KI with wide expertise in database structures and biocomputational approaches.

Dr Litton is director of informatics of KI Biobank and the database core of GenomEUtwin, and Dr Palmgren is also co-ordinator of Bioinformatics Platform of the Wallenberg Consortium North. Their expertise will be complemented by database and statistical expertise in other four centers. The core will organize annual database meetings to bring together the database experts and database maintenance staff from all participating centers. They will be responsible for the website of the NCoEDG and together with human and animal genetics cores create two databases funded by the NCoEDG.

(Leaders Juha Kere and Juni Palmgren)