The genetic background of common health problems like metabolic syndrome, diabetes, asthma, autoimmune diseases and colon cancer has remained unsolved despite of efforts of numerous research groups during past decades. The recently completed genome projects of human and other species have however transformed our possibilities to identify disease genes and characterize the risks of common diseases at the genome-wide level (all genetic elements critical for the disease outcome can be identified). This understanding will increase our possibilities to provide a more accurate disease diagnosis and eventually result in better targeted treatment and care. Some genetic inventions are expected to dramatically increase our possibilities to develop new drugs and other treatments for many, often old age-onset diseases which represent a burden for individuals and societies. Since genetic background of common diseases is complex, large study samples from different populations and model organisms as well as novel molecular and computational technologies are needed for disease gene characterization.

The Nordic Centre of Excellence in Disease Genetics aims to work like one integrated research group being linked virtually and via multiple annual workshops. Students and scientists will visit other Nordic laboratories and the training program will educate a generation of young scientists in new genome-wide approaches. The Center aims to create a unique scientific environment which could attract scientists and students also from outside Nordic countries. This would maximize our possibilities to solve the molecular background of these common diseases and use the inventions for the betterment of Nordic societies and health care.